Paleogenomics of the Plague Agent and Prospects for Paleogenomic Studies in Russia

The review contains information on paleogenomic studies of the plague pathogen, Yersinia pestis , covering prehistoric epoch, periods first and second pandemics, epidemics outbreaks late XIX–XX centuries. We have summarized data reconstruction ancient Y. genomes Late Neolithic, Bronze Iron Ages, Justinian Plague epidemic pandemic, Black Death subsequent pandemic XIV–XVIII centuries, as well tracing pathways propagation waves in Eurasia course agent evolution with formation a vector-borne transmission route help arthropods. present results our own research from key sites etiological agents pandemics Tien Shan Mountains, historical Northern North-Western Caspian sea region other regions Russia adjoining countries paper discusses areas Caucasus, Crimea, Caspian, Siberia, territory neighboring states that are promising for national plague.